Clinical

Prescribe from the chart, including controlled substances.

Full e-prescribing with EPCS for buprenorphine and other controlled medications, with the medication list, allergies, and interaction checks on the same record as the treatment plan.

See what it costs

MAT-ready. Built for programs prescribing buprenorphine and naltrexone.

Chain of custody

Every controlled prescription passes the same five checkpoints.

EPCS is a regulated workflow, not a feature toggle. Each step is enforced in order and logged, so the record of how a buprenorphine prescription was issued is as complete as the prescription itself.

  1. Identity proofing

    The prescriber completes one-time identity verification and is issued two-factor credentials.

    Once, at enrollment
  2. PDMP check

    State prescription drug monitoring lookup before the controlled prescription is written, with the result recorded on the chart.

    Every controlled prescription
  3. Clinical checks

    Allergies, drug interactions, and duplicate therapy checked against the same medication list the clinical team maintains.

    Automatic
  4. Two-factor signing

    The prescriber authenticates a second time at the moment of signature. Nobody else can sign on their behalf.

    At signature
  5. Transmission and log

    Sent to the pharmacy electronically. Prescriber, timestamp, PDMP result, and destination are written to the activity log.

    Immutable
Prescriptioncontrolled · schedule III
MedicationBuprenorphine/naloxone 8-2mg
Sig1 film SL daily
Quantity30 · 30 days
Refills2
PDMP checked09/02/26
Interactionsnone flagged
Transmitted · Walgreens #4412

Non-controlled prescribing, refill requests, and pharmacy change requests run through the same queue without the additional steps.

Why this decides the platform

A MAT program can't run on a system that stops at non-controlled medications.

Office-based opioid treatment and opioid treatment programs prescribe controlled substances as the core of the clinical model. If EPCS lives in a second system, so does the medication list — and then so does the reconciliation problem.

In the same record

The medication list is one list

Home medications, prescribed medications, and — in residential settings — administered medications reconcile against each other because they are not in three systems.

In the same log

The audit trail is one trail

Prescribing activity appears in the same immutable activity log as chart access and record exports, which is what a DEA or state inspection expects to see.

Live today

EPCS is live, not on the roadmap.

Controlled prescribing is available now, in the same record as the treatment plan. The only setup is per prescriber: one-time identity proofing and two-factor credentials, after which every controlled prescription passes the same five enforced checkpoints.

5enforced checkpoints

Questions

Common questions.

Does Unisona Health support EPCS for controlled substances?

Yes. Controlled prescriptions pass five enforced checkpoints in order: one-time identity proofing with two-factor credentials, a PDMP check recorded on the chart, automatic allergy and interaction checks, two-factor signing at the moment of signature, and electronic transmission written to the immutable activity log.

Can I prescribe buprenorphine for a MAT program?

Yes. Prescribing buprenorphine under EPCS, alongside non-controlled MAT medications such as naltrexone, is the core clinical model, not a bolt-on, so the medication list stays in one place instead of splitting across a second system and creating a reconciliation problem.

Is a PDMP check required before a controlled prescription?

Yes. The state PDMP lookup happens before the controlled prescription is written and its result is recorded on the chart, alongside allergy, interaction and duplicate-therapy checks against the same medication list the clinical team maintains.

Is EPCS fully live today?

Yes. EPCS is live today for buprenorphine and other controlled medications. Each prescriber completes a one-time enrollment, with identity proofing and two-factor credentials, before their first controlled prescription; after that, every controlled prescription passes the same five enforced checkpoints, including the PDMP check.

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